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EP285 The impact of socioeconomic deprivation on survival in cervical cancer patients: a systematic review
  1. H Donkers1,
  2. R Bekkers2,
  3. L Massuger2 and
  4. K Galaal3
  1. 1Gynae-Oncology, Royal Cornwall Hospital, Truro, UK
  2. 2Radboud UMC Nijmegen, Nijmegen, The Netherlands
  3. 3Royal Cornwall Hospital Trust, Truro, UK


Introduction/Background Factors that increase the risk of cervical cancer are more frequently seen in socioeconomically deprived patients. Furthermore, socioeconomic deprivation is associated with decreased survival in most cancers, mainly due to an advanced stage at diagnosis for more deprived patients. However, in cervical cancer this association is unclear.

Methodology We performed a systematic search of Medline (1946–2018), Embase (1980–2018), Cinahl (1981–2018) and the Cochrane Controlled Register of trials to identify studies that reported on the association between socioeconomic deprivation and survival in cervical cancer patients. Included were adult women (age ≥18 years) diagnosed with primary cervical cancer. Two reviewers independently selected studies and assessed bias using the Newcastle-Ottawa assessment scale. Data extraction was completed using pre-determined forms and summary tables of evidences from the included studies were created.

Results Eight studies were included in this review with a total number of at least 38,811 patients. All eight studies showed that socioeconomic deprivation is associated with poorer survival in cervical cancer patients with five studies confirming this association in multivariate analysis.

Conclusion Socioeconomic deprivation is associated with survival in cervical cancer patients, in which more deprived patients have worse survival. Further research should focus on the interaction between cervical screening attendance, smoking status, stage at diagnosis, socioeconomic deprivation and survival in cervical cancer patients.

Disclosure Nothing to disclose.

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