Introduction/Background After the published guidelinesof Group Européen de Curiethérapie and European Society for Radiotherapy andOncology (GEC-ESTRO) for tridimensional image-guided brachytherapy, many cancercenters have started abandoning the bidimensional conventional brachytherapy(2D-BT). The purpose of this study was to analyze the transition from 2D-BT totridimensional computed tomography-guided brachytherapy (CT-BT) and its effectson target and organs at risk in cervical cancer patients treated in ourinstitution.
Methodology We performed a retrospectiveanalysis of 308 patients diagnosed with cervical cancer between 2016 and 2018.All patients were treated with primary chemoradiation, followed by CT-BT. Foreach patient we used a tandem-ring applicator and retrospectively realized one2D-BT plan with dose prescribed in International Commission on Radiation Unitsand Measurements (ICRU) point A and equal dwell times and a second plan withdose prescribed to the high-risk clinical target volume (HR-CTV) and differentdwell times.
Results When prescribed to ICRUreference points, the mean dose to point A was 99.88% of the prescription dose(PD), the mean ICRU bladder and rectum point dose was 102.38% and 100.79% ofPD, respectively. When prescribed to HR-CTV, the mean dose to irradiated volumewas 96.6% of the PD, mean D2cc for bladder and rectum was 86.76% and 65.58% ofPD, respectively. Mean volume of 100% dose was 106.5cc vs 78.25cc whenprescribing to point A vs HR-CTV.
Conclusion The study showed a reduction ofthe irradiated volume by 23.3% when the prescription of dose was done to HR-CTVcompared to point A, the D2cc for bladder and rectum were also lowered. Inconclusion, the old and never-ending love story of 2D-BT and CT-BT has to cometo an end in our institution, in order for the tridimensional image-guidedbrachytherapy techniques to write their own story and for cervical cancer tostop getting the principal role.
Disclosure Nothing to disclose.
Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.