Introduction/Background The objective was to describe the prognostic factors in locoregional recurrence of breast cancer in our context.

Methodology We conducted retrospective study in patients diagnosed or treated for breast cancer between January 2016 and December 2017.

To obtain significant results we have deferred to the statistical rules.

Results During the study period, 703 cases of breast cancer were collected, 47 cases have developed locoregional recurrence. The average time of recurrence was 42 months. The average tumor size was 3.5 The occurrence of recurrence was also correlated with an advanced stage of tumor up to 42.6% in stage II, infiltrating ductal carcinoma was found in (91.4%) with a predominant SBR II grade in (55.3%), as well as the Presence of vascular emboli (47%), lymph node involvement in (38.3%), Of 34 analyzed tumors, 11% were classified as luminal A, 9% as luminal B 6% as Her-2 type, and 15% as Basal type. Radical Patey treatment was performed in 24 patients, 17% of whom received neoadjuvant chemotherapy, 32%received adjuvant radiotherapy, 17% had an hormonal treatment and 6.3% received targeted therapies. The 23 patients were treated by a conservative treatment which (44.6%) patients have benefited radiotherapy and (38.2%) patients have received adjuvant chemotherapy and 12.7% had an hormonal treatment.

Conclusion Although enormous progress has been made in understand of the biology of breast cancer and its heterogeneity, there is still much to do to be able to distinguish patients at high risk of recurrence requiring more crucial treatment.

Disclosure Nothing to disclose.