P119 An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

O Kopper; CJ de Witte; K Lõhmussaar; J Espejo Valle-Inclan; N Hami; L Kester; AV Balgobind; J Korving; N Proost; H Begthel; LM van Wijk; SA Revilla; R Theeuwsen; M van de Ven; MJ van Roosmalen; B Ponsioen; VWH Ho; BG Neel; T Bosse; KN Gaarenstroom; H Vrieling; MPG Vreeswijk; PJ van Diest; PO Witteveen; T Jonges; JL Bos; A van Oudenaarden; RP Zweemer; HJG Snippert; WP Kloosterman; H Clevers

doi:10.1136/ijgc-2019-ESGO.182

Article info

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P119 An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

Authors

O Kopper Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and UMC Utrecht Oncode Institute PubMed articles Google scholar articles
CJ de Witte Oncode Institute Center for Molecular Medicine PubMed articles Google scholar articles
K Lõhmussaar Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and UMC Utrecht Oncode Institute PubMed articles Google scholar articles
J Espejo Valle-Inclan Oncode Institute Center for Molecular Medicine PubMed articles Google scholar articles
N Hami Oncode Institute Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht PubMed articles Google scholar articles
L Kester Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and UMC Utrecht Oncode Institute PubMed articles Google scholar articles
AV Balgobind Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and UMC Utrecht Oncode Institute PubMed articles Google scholar articles
J Korving Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and UMC Utrecht Oncode Institute PubMed articles Google scholar articles
N Proost Preclinical Intervention Unit of the Mouse Clinic for Cancer and Ageing (MCCA), Netherlands Cancer Institute, Amsterdam PubMed articles Google scholar articles
H Begthel Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and UMC Utrecht Oncode Institute PubMed articles Google scholar articles
LM van Wijk Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands PubMed articles Google scholar articles
SA Revilla Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and UMC Utrecht Oncode Institute PubMed articles Google scholar articles
R Theeuwsen Preclinical Intervention Unit of the Mouse Clinic for Cancer and Ageing (MCCA), Netherlands Cancer Institute, Amsterdam PubMed articles Google scholar articles
M van de Ven Preclinical Intervention Unit of the Mouse Clinic for Cancer and Ageing (MCCA), Netherlands Cancer Institute, Amsterdam PubMed articles Google scholar articles
MJ van Roosmalen Center for Molecular Medicine PubMed articles Google scholar articles
B Ponsioen Oncode Institute Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht PubMed articles Google scholar articles
VWH Ho Princess Margaret Cancer Center, University Health Network, Toronto, ON, Canada PubMed articles Google scholar articles
BG Neel Princess Margaret Cancer Center, University Health Network, Toronto, ON, Canada Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA PubMed articles Google scholar articles
T Bosse Department of Pathology, Leiden University Medical Center, Leiden PubMed articles Google scholar articles
KN Gaarenstroom Department of Pathology, Leiden University Medical Center, Leiden PubMed articles Google scholar articles
H Vrieling Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands PubMed articles Google scholar articles
MPG Vreeswijk Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands PubMed articles Google scholar articles
PJ van Diest Department of Pathology PubMed articles Google scholar articles
PO Witteveen Department of Medical Oncology, Cancer Center PubMed articles Google scholar articles
T Jonges Department of Pathology PubMed articles Google scholar articles
JL Bos Oncode Institute Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht PubMed articles Google scholar articles
A van Oudenaarden Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and UMC Utrecht Oncode Institute PubMed articles Google scholar articles
RP Zweemer Department of Gynaecological Oncology, Cancer Center, University Medical Center Utrecht, Utrecht University PubMed articles Google scholar articles
HJG Snippert Oncode Institute Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht PubMed articles Google scholar articles
WP Kloosterman Center for Molecular Medicine PubMed articles Google scholar articles
H Clevers Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and UMC Utrecht Oncode Institute The Netherlands Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands PubMed articles Google scholar articles

Citation

Kopper O, de Witte C, Lõhmussaar K, et al

P119 An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

International Journal of Gynecologic Cancer 2019;29:A132.

Publication history

First published November 1, 2019.

Online issue publication

March 03, 2020

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