TP53 mutations in cell-free DNA as early markers of therapeutic response in platinum-resistant relapsed ovarian cancer (PROC): a prospective translational analysis of the phase II GANNET53 clinical trial

A Vanderstichele; N Concin; P Busschaert; I Braicu; P Combe; I Ray-Coquard; F Joly; P Harter; P Wimberger; F Selle; A Ignatov; B Schmalfeldt; E Van Nieuwenhuysen; S Darb-Esfahani; A Zeimet; S Mahner; E Pujade-Lauraine; C Marth; R Berger; J Sehouli; U Moll; R Zeillinger; D Lambrechts; I Vergote

doi:10.1136/ijgc-2019-ESGO.11

Article info

Best Oral Communications/Late-Breaking Abstracts 3 – Ovarian Cancer

TP53 mutations in cell-free DNA as early markers of therapeutic response in platinum-resistant relapsed ovarian cancer (PROC): a prospective translational analysis of the phase II GANNET53 clinical trial

Authors

A Vanderstichele Division of Gynaecological Oncology, University Hospitals Leuven, and Department of Oncology, Leuven Cancer Institute, KU Leuven, Leuven, European Union, Belgium PubMed articles Google scholar articles
N Concin Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
P Busschaert Division of Gynaecological Oncology, University Hospitals Leuven, and Department of Oncology, Leuven Cancer Institute, KU Leuven, Leuven, European Union, Belgium PubMed articles Google scholar articles
I Braicu Charite Medical University of Berlin, Berlin, Germany PubMed articles Google scholar articles
P Combe Assistance Publique des Hôpitaux de Paris (AP-HP), Paris PubMed articles Google scholar articles
I Ray-Coquard Centre Anticancereux Léon Bérard, Lyon PubMed articles Google scholar articles
F Joly Centre de Lutte Contre le Cancer, Francois Baclesse, Caen, France PubMed articles Google scholar articles
P Harter Klinik Essen-Mitte, Essen PubMed articles Google scholar articles
P Wimberger Technische Universität Dresden University Hospital, Dresden PubMed articles Google scholar articles
F Selle Assistance Publique des Hôpitaux de Paris (AP-HP), Paris PubMed articles Google scholar articles
A Ignatov Otto-von-Guericke-Universität Magdeburg, Magdeburg PubMed articles Google scholar articles
B Schmalfeldt Universitätsklinikum Hamburg-Eppendorf, Hamburg PubMed articles Google scholar articles
E Van Nieuwenhuysen Division of Gynaecological Oncology, University Hospitals Leuven, and Department of Oncology, Leuven Cancer Institute, KU Leuven, Leuven, European Union, Belgium PubMed articles Google scholar articles
S Darb-Esfahani Charite Medical University of Berlin, Berlin, Germany PubMed articles Google scholar articles
A Zeimet Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
S Mahner Universitätsklinikum Hamburg-Eppendorf, Hamburg Ludwig Maximilian University of Munich, Munich, Germany PubMed articles Google scholar articles
E Pujade-Lauraine Assistance Publique des Hôpitaux de Paris (AP-HP), Paris PubMed articles Google scholar articles
C Marth Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
R Berger Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
J Sehouli Charite Medical University of Berlin, Berlin, Germany PubMed articles Google scholar articles
U Moll Department of Pathology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA PubMed articles Google scholar articles
R Zeillinger Molecular Oncology Group, Medical University of Vienna, Vienna, Austria PubMed articles Google scholar articles
D Lambrechts Laboratory for Translational Genetics, Department of Oncology Center for Cancer Biology, VIB, KU Leuven, Leuven, Belgium PubMed articles Google scholar articles
I Vergote Division of Gynaecological Oncology, University Hospitals Leuven, and Department of Oncology, Leuven Cancer Institute, KU Leuven, Leuven, European Union, Belgium PubMed articles Google scholar articles

Citation

Vanderstichele A, Concin N, Busschaert P, et al

International Journal of Gynecologic Cancer 2019;29:A11.

Publication history

First published November 1, 2019.

Online issue publication

March 03, 2020

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