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150 The outcome of treatment in advanced carcinoma cervix with hydronephrosis
  1. D Barmon1,
  2. A Kataki1,
  3. M Nandwani1 and
  4. M Kalita2
  1. 1Dr B. Borooah Cancer Institute, Gynaecologic Oncology, Guwahati, India
  2. 2Dr B. Borooah Cancer Institute, Statistics, Guwahati, India


Objectives Aim of the study is to find out the final outcome of the two treatment groups comprising of the RT alone and concommitant CT-RT in diagnosed case of advanced carcinoma cervix with hydronephrosis.

Methods It is a retrospective study where diagnosed cases of Ca Cervix IIIB with tumor size more than 4 cms and presence of hydronephrosis with normal renal functions, attending our OPD from Jan 2012 to December 2015 were included in the study. Altogather 80 patients fulfilled the inclusion criteria and the patients were divided into two groups depending on the plan of treatment 36 patients received only RT whereas 44 patients received concomitant CT RT All the patients were evaluated after completion of treatment and followed up regularly.

Results Altogather 70 patients completed the prescribed treatment, out of the 36 patients in RT group 5.6% of the patients dropped out and of the 44 patients in the concommitant CT-RT group, there was a dropout of 18.2% of patients. Seventy percent of all the dropout were found when the tumor size was more than 8cms. The 5 yr. overall survival for all patients was 40.6% and the median survival was 39.0 months (95% CI, 27.4 - 50.6). The OS in the RT group was 34.4% whereas in the concommitant CT-RT group it was 47.0% (p value = 0.041).

Conclusions Concurrent CTRT can be given in selected cases of advanced carcinoma cervix with hydronephrosis resulting in survival advantage when compared with RTalone.

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