76 Patients (PTS) with recurrent gynecologic cancer whose tumors have activating wnt pathway mutations respond better to DKN-01, a DICKKOPF-1 (DKK1) inhibitor

R Arend; C Castro; U Matulonis; E Hamilton; C Gunderson; K LyBarger; H Goodman; L Duska; H Mahdi; A ElNaggar; M Kagey; L Barroilhet; W Bradley; J Sachdev; D O’Malley; C Sirard; M Birrer

doi:10.1136/ijgc-2019-IGCS.76

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76 Patients (PTS) with recurrent gynecologic cancer whose tumors have activating wnt pathway mutations respond better to DKN-01, a DICKKOPF-1 (DKK1) inhibitor

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Authors

R Arend 1University of Alabama at Birmingham, Gynecologic Oncology, Birmingham, USA PubMed articles Google scholar articles
C Castro 2Massachusetts General Hospital, Hematology/Oncology, Boston, USA PubMed articles Google scholar articles
U Matulonis 3Dana Farber Cancer Institute, Gynecologic Oncology, Boston, USA PubMed articles Google scholar articles
E Hamilton 4Sarah Cannon Research Institute/Tennessee Oncology, Breast and Gynecologic Cancer Research Program, Nashville, USA PubMed articles Google scholar articles
C Gunderson 5The University of Oklahoma Health Sciences Center, Gynecologic Oncology, Oklahoma City, USA PubMed articles Google scholar articles
K LyBarger 6Sarah Cannon Research Institute at HCA Midwest, Gynecologic Oncology, Kansas City, USA PubMed articles Google scholar articles
H Goodman 7Florida Cancer Specialists, Gynecologic Oncology, West Palm Beach, USA PubMed articles Google scholar articles
L Duska 8University of Virginia Health System, Gynecologic Oncology, Charlottesville, USA PubMed articles Google scholar articles
H Mahdi 9Cleveland Clinic, Gynecologic Oncology, Cleveland, USA PubMed articles Google scholar articles
A ElNaggar 10West Cancer Clinic, Gynecologic Oncology, Memphis, USA PubMed articles Google scholar articles
M Kagey 11Leap Therapeutics- Inc., Research, Cambridge, USA PubMed articles Google scholar articles
L Barroilhet 12University of Wisconsin Hospitals and Clinics, Gynecologic Oncology, Madison, USA PubMed articles Google scholar articles
W Bradley 13Froedtert and Medical College of Wisconsin, Gynecology/Oncology, Milwaukee, USA PubMed articles Google scholar articles
J Sachdev 14HonorHealth Research Institute, Hematology/Oncology, Scottsdale, USA PubMed articles Google scholar articles
D O’Malley 15Ohio State University, Gynecologic Oncology, Columbus, USA PubMed articles Google scholar articles
C Sirard 16Leap Therapeutics- Inc., Clinical Research, Cambridge, USA PubMed articles Google scholar articles
M Birrer 1University of Alabama at Birmingham, Gynecologic Oncology, Birmingham, USA PubMed articles Google scholar articles

Citation

Arend R, Castro C, Matulonis U, et al

76 Patients (PTS) with recurrent gynecologic cancer whose tumors have activating wnt pathway mutations respond better to DKN-01, a DICKKOPF-1 (DKK1) inhibitor

International Journal of Gynecologic Cancer 2019;29:A40-A41.

Publication history

First published September 18, 2019.

Online issue publication

September 18, 2019

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