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418 Prognostic factors and patterns of recurrence among patients treated for endometrial cancer in southern Brazil
  1. G Carvalho1,
  2. MBDMP Salcedo2 and
  3. SA Pessini3
  1. 1Hospital Escola da Universidade Federal de Pelotas HE-UFPEL, Ginecologia e Obstetrícia, Pelotas, Brazil
  2. 2Universidade Federal de Ciências da Saúde de Porto Alegre UFCSPA, Ginecologia e Obstetrícia, Porto Alegre, Brazil
  3. 3Universidade Federal do Rio Grande do Sul UFRGS, Ginecologia e Obstetrícia, Porto Alegre, Brazil


Objectives To compare the clinical and histopathological characteristics of women with and without recurrence of endometrial cancer after primary surgical treatment.

Methods A retrospective cohort study was carried out in Irmandade Santa Casa de Misericórdia de Porto Alegre (ISCMPA) with patients treated for endometrial cancer from 1995 to 2016, in Southern Brazil.

Cox regression was used to identify independent prognostic factors and survival was calculated by using the Kaplan-Meier method.

Results 216 women were submitted to surgical treatment for endometrial carcinoma and met the criteria for inclusion in the study. 23 (10.6%) participants have developed recurrent disease after a mean time of 3.7 years (SD ± 4.2). Depth of myometrial infiltration, stromal cervical involvement, FIGO staging and death were variables that presented a statistically significant difference between patients with and without recurrence.

Conclusions This study ratifies the depth of myometrial infiltration greater than 50%, cervical stromal invasion and staging according to FIGO 2009 criteria are important prognostic factors in the recurrence of endometrial cancer. The recurrence of this tumor is related to a reduction in overall survival. These data are compatible with the existing literature and complement the scarce casuistica on endometrial cancer in Brazil.

Acknowledgments To the entire gynecologic oncology group of ISCMPA, especially Professor Gustavo Py Gomes da Silveira.

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