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TP53 mutations in high grade serous ovarian cancer and impact on clinical outcomes: a comparison of next generation sequencing and bioinformatics analyses
  1. Victoria Mandilaras1,
  2. Swati Garg2,
  3. Michael Cabanero3,
  4. Qian Tan1,
  5. Chiara Pastrello4,
  6. Julia Burnier1,
  7. Katherine Karakasis1,
  8. Lisa Wang1,
  9. Neesha C Dhani1,
  10. Marcus O Butler1,
  11. Philippe L Bedard1,
  12. Lillian L Siu1,
  13. Blaise Clarke3,
  14. Patricia Ann Shaw3,
  15. Tracy Stockley2,
  16. Igor Jurisica4,5,6,
  17. Amit M Oza1 and
  18. Stephanie Lheureux1
  1. 1 Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada
  2. 2 Advanced Molecular Diagnostics Laboratory, Princess Margaret Cancer Centre, Toronto, Ontario, Canada
  3. 3 Department of Laboratory Medicine and Pathology, University Health Network, Toronto, Ontario, Canada
  4. 4 Krembil Research Institute, University Health Network, Toronto, Ontario, Canada
  5. 5 Departments of Medical Biophysics and Computer Science, University of Toronto, Toronto, Ontario, Canada
  6. 6 Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia
  1. Correspondence to Stephanie Lheureux, Division on Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON M5G 2M9, Canada; stephanie.lheureux{at}uhn.ca

Footnotes

  • Funding This study was funded by the Pamela Mary Hosang Ovarian Cancer Research Fund at The Princess Margaret Cancer Foundation, the Cedars Cancer Foundation Henry R Shibata Fellowship, and the Ontario Research Fund (#34876).

  • Competing interests None declared.

  • Provenance and peer review Not commissioned, externally peer reviewed.

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Footnotes

  • Funding This study was funded by the Pamela Mary Hosang Ovarian Cancer Research Fund at The Princess Margaret Cancer Foundation, the Cedars Cancer Foundation Henry R Shibata Fellowship, and the Ontario Research Fund (#34876).

  • Competing interests None declared.

  • Provenance and peer review Not commissioned, externally peer reviewed.

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