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Abdominal Radical Trachelectomy for Early-Stage Cervical Cancer During Pregnancy: A Provocative Surgical Approach. Overview of the Literature and a Single-Institute Experience
  1. Alexandros Rodolakis, MD, PhD*,
  2. Nikolaos Thomakos, MD, PhD*,
  3. Maria Sotiropoulou, MD, PhD,
  4. Konstantinos Kypriotis, MD*,
  5. Dimitrios Valsamidis, MD, PhD,
  6. Charis Bourgioti, MD§,
  7. Lia Evangelia Moulopoulou, MD, PhD§,
  8. Georgios Vlachos, MD, PhD* and
  9. Dimitrios Loutradis, MD, PhD*
  1. *1st Obstetric and Gynaecological Department of “Alexandra” Hospital of National and Kapodistrian University of Athens, Athens, Greece.
  2. Department of Histopathology and Kapodistrian University of Athens, Athens, Greece.
  3. Department of Anesthesiology, “Alexandra” General Hospital, Kapodistrian University of Athens, Athens, Greece.
  4. §Department of Radiology “Aretaieion” Hospital of National and Kapodistrian University of Athens, Athens, Greece.
  1. Address correspondence and reprint requests to Konstantinos Kypriotis, MD, 1st Obstetric and Gynaecological Department “Alexandra” Hospital of National and Kapodistrian University of Athens, Konstantinoupoleos 36, Nea Penteli, Athens, Greece 15236. E-mail: kypriotisk{at}


Objective Treatment of pregnancy complication due to malignancy of the cervix constitutes a great clinical challenge between optimal maternal therapy and fetal viability. Radical trachelectomy in early-stage cervical cancer during pregnancy instead of radical hysterectomy presents an alternative approach that can offer a satisfactory outcome for the mother and fetus.

Materials and Methods–Results A literature search of articles in English has been performed. Until now, 28 women with cervical cancer, including 2 who were managed and treated in our institute, who underwent a radical trachelectomy during pregnancy have been reported. We overviewed a total of 13 abdominal trachelectomies, 13 vaginal trachelectomies, and 2 laparoscopic trachelectomies.

Conclusions Radical trachelectomy can widen the therapeutic approach of early-stage cervical cancer in pregnant women who wish to preserve their pregnancy, providing a possibility of receiving the proper treatment with no delay.

  • Pregnancy
  • Cervical cancer
  • Radical trachelectomy

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