Article Text

Download PDFPDF
Incidence Patterns and Survival of Gynecological Sarcoma in Germany: Analysis of Population-Based Cancer Registry Data on 1066 Women
  1. Klaus Pietzner, MD*,
  2. Nina Buttmann-Schweiger, MPH,
  3. Jalid Sehouli, MD, PhD* and
  4. Klaus Kraywinkel, MD
  1. * Department of Gynecology, European Competence Centre for Ovarian Cancer and Rare Tumors (EKZE), Charite—University Medicine of Berlin; and
  2. Department of Epidemiology and Health Monitoring, German Centre for Cancer Registry Data (ZfKD), Robert Koch-Institute, Berlin, Germany.
  1. Address correspondence and reprint requests to Klaus Pietzner, MD, Department of Gynecology, European Competence Centre for Ovarian Cancer and Rare Tumors (EKZE), Charite—University Medicine of Berlin, Augustenburger Platz 1, 13353 Berlin, Germany. E-mail: klaus.pietzner{at}


Objective Sarcomas of the female genital tract are rare tumors. They are described to be associated with a poor prognosis when compared with gynecogical carcinoma. The aim of this study was to report incidence patterns and survival rates for gynecological sarcoma (GS) in Germany.

Methods/Materials Clinical data and survival rates for patients with GS diagnosed in Germany between 2009 and 2013 were extracted from the German national center for population-based cancer registry data. Incidence patterns and 5-year relative survival rates were calculated.

Results A total of 1066 GSs were included in our analysis during a 5-year time span. The uterus was the most common site, with 87.9% of all cases. The annual age-standardized incidence rate (old European standard) was 8.7 per 1 million women for all GSs. The median age at diagnosis was 59 years. The prognosis ranged according to site, stage, and subtype, for example, from a 5-year relative survival of 53.0% (uterine leiomyosarcoma) if confined to the pelvis, to a very good 5-year relative survival of 97.2% (endometrial stromal sarcoma).

Conclusions Despite the rareness of GS, the size of the data set allows for a differentiation of subtypes according to morphology and site of origin. Clinically relevant differences in incidence and prognosis between subgroups were observed.

  • Gynecological sarcoma
  • Incidence
  • Population based

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • The authors declare no conflicts of interest.