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Does BLOODCARE Powder Prevent Postoperative Chylous Ascites After Lymphadenectomy for Gynecological Malignancies?
  1. Kemal Güngördük, MD*,
  2. Özgü Celikkol Güngördük, MD,
  3. I. Aykut Ozdemir, MD,
  4. Mehmet Gokcu, MD§ and
  5. Muzaffer Sanci, MD
  1. * Departments of Gynecologic Oncology and
  2. Obstetrics and Gynecology, Muğla Education and Research Hospital, Muğla,
  3. Department of Gynecologic Oncology, Bakirköy Dr. Sadi Konuk Education and Research Hospital, İstanbul; and
  4. § Department of Gynecologic Oncology, Tepecik Education and Research Hospital, İzmir, Turkey.
  1. Address correspondence and reprint requests to Kemal Güngördük, MD, Department of Gynecologic Oncology, Muğla Education and Research Hospital, Mentese, 4800 Muğla, Turkey. E-mail: drkemalgungorduk{at}


Objective The aim of this study was to evaluate the effect of an intraoperative hemostatic cellulose agent (BLOODCARE powder [Life Line, Brno, Czech Republic]) on reducing the incidence of postoperative chylous ascites (PCA) after complete pelvic and para-aortic lymphadenectomy (PPALN) in patients with gynecological cancers treated with laparotomy.

Methods This case control study reviewed 150 patients with gynecological cancer who underwent PPALN. In the study group (n = 75), BLOODCARE powder was applied below the left renal vein and bilateral obturator fossa. In the control group (n = 75), no sealant agent was used after the procedure, such as fibrin glue or a hemostatic cellulose agent.

Results The demographic and surgical characteristics of the patients in both groups were similar. Chylous ascites occurred in 9 cases (6%). The incidence of PCA was lower in the study group (1 [1.3%] vs 8 [10.7%]; P = 0.03). Logistic regression analysis indicated that using BLOODCARE powder during the surgery independently protected against the development of PCA.

Conclusions Using BLOODCARE powder during retroperitoneal surgery may prevent PCA. This simple, effective agent should be used after PPALN for gynecological cancers.

  • BLOODCARE powder
  • Chylous ascites
  • Gynecological cancers
  • Lymphadenectomy

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  • The authors declare no conflicts of interest.