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Sexual Function and Quality of Life Among Patients With Endometrial Cancer After Surgery
  1. Huiqiao Gao, MD,
  2. Meizhu Xiao, MM,
  3. Huimin Bai, MD and
  4. Zhenyu Zhang, MD
  1. Department of Obstetrics and Gynecology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
  1. Address correspondence and reprint requests to Zhenyu Zhang, MD, Capital Medical University, No. 8, Gongti South Road, Chaoyang District, Beijing 100020, China. E-mail:


Objective The aim of this study was to evaluate the sexual function and quality of life (QOL) and identify their associated factors in survivors of endometrial cancer.

Methods The participants in this study were survivors of endometrial cancer who visited the gynecological outpatient department for routine surveillance from June 2014 to May 2015. The QOL and sexual function were measured using the Functional Assessment of Cancer Therapy–General (FACT-G) and Female Sexual Function Index questionnaires. A score less than 26.55 was defined as female sexual dysfunction (FSD). Multivariate analysis and logistic regression were performed to identify the factors associated with QOL and sexual function.

Results A total of 118 women completed the questionnaires. The results revealed that 68.6% of the patients had FSD and that 55.9% of the patients never had sexual intercourse with their partners after surgery. Age, followed by time after surgery, radiotherapy, and consultation, was significantly correlated with FSD. The median score of the FACT-G was 86 (range, 41–108). Chemotherapy and marital status were found to significantly impair physical and social/family well-being, respectively (P < 0.05), and monthly income was identified as a factor that significantly affected the total FACT-G scores.

Conclusion The risk factors associated with FSD and QOL need to be studied in greater detail. Prospective researches that evaluate the effects of clinical psychological intervention on sexual function may be needed in the future.

  • Endometrial cancer
  • Sexual function
  • Quality of life

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  • This study was supported in part by the Chinese High-tech R&D (863) Program.

  • The authors declare no conflicts of interest.