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Utility of Laparoscopic Indocyanine Green-Guided Sentinel Node Biopsy in Open Cervical Cancer Surgery
  1. Agnieszka Rychlik, MD,
  2. Silvia Marin, MD,
  3. Javier De Santiago, MD, PhD and
  4. Ignacio Zapardiel, MD, PhD
  1. Gynecologic Oncology Unit, La Paz University Hospital, Madrid, Spain.
  1. Address correspondence and reprint requests to Ignacio Zapardiel, MD, PhD, Gynecologic Oncology Unit, La Paz University Hospital, Paseo de la Castellana 261, 28046, Madrid, Spain. E-mail:


Objective Multiple tracers have been used to improve lymphatic mapping and to reduce the false-negative rate of the sentinel node detection in gynecologic cancers. Nowadays, 99mTc colloids combined with blue-dye technique is the most extended technique. New alternatives such as the fluorescent indocyanine green and near-infrared fluorescent imaging detection have been introduced in lymphatic mapping staging procedures because of its easier visualization compared with the previous tracers.

Methods We used the laparoscopic infrared camera for the indocyanine green-guided sentinel node biopsy in a laparotomic radical hysterectomy in a pregnant patient after a cesarean section, with the aim of improving the detection rate of sentinel node biopsy in open surgery.

Results The technique was used in the first patient with accurate detection of sentinel node and no complications during the procedure.

Conclusions The use of laparoscopic indocyanine green in open surgery may be a useful tool for the detection of sentinel node biopsy.

  • Sentinel node biopsy
  • Indocyanine green
  • Laparoscopic surgery
  • Cervical cancer

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  • The authors have no commercial, proprietary, or financial interest in the products or companies described in this article. No funds have been received from any of the following organizations: National Institutes of Health, Wellcome Trust, Howard Hughes Medical Institute, and others.

  • The authors declare no conflicts of interest.

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