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Does a Standardized Preoperative Algorithm of Clinical Data Improve Outcomes in Patients With Ovarian Cancer? A Quality Improvement Project
  1. Monjri M. Shah, MD*,
  2. Charles A. Leath, MD, MSPH*,
  3. Laura Rebecca Daily, MD*,
  4. Gerald McGwin, PhD,
  5. Jacob M. Estes, MD*,
  6. Ronald D. Alvarez, MD, MBA* and
  7. John Michael Straughn, MD*
  1. *Departments of Obstetrics and Gynecology and
  2. Departments of Epidemiology, University of Alabama at Birmingham, Birmingham, AL.
  1. Address correspondence and reprint requests to J. Michael Straughn, Jr, MD, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 1700 6th Ave South, Room 10250, Birmingham, AL 35233. E-mail:


Objective To evaluate the potential impact of a standardized preoperative algorithm on outcomes of patients with suspected ovarian cancer.

Methods From January 1 to December 31, 2013, patients with suspected ovarian cancer were triaged to primary debulking surgery or neoadjuvant chemotherapy/interval debulking surgery (NACT/IDS) based on a comprehensive review of preoperative clinical data as part of a quality improvement project. Demographics, surgical, and postoperative data were collected.

Results A total of 110 patients with newly diagnosed ovarian cancer were identified: 68 (62%) underwent PDS with an 85% optimal debulking rate. The 30-day readmission rate was 14.7% with a 2.9% 60-day mortality rate. Forty-two patients (38%) underwent NACT. Two patients (4.8%) died before receiving NACT. Thirty-five patients have undergone IDS with an 89% optimal debulking rate. The 30-day readmission rate was 8.5% with a 5.7% 60-day mortality rate after IDS.

Conclusions Although it is difficult to predict which patients will undergo optimal debulking at the time of PDS, surgical morbidity and mortality can be decreased by using NACT in select patients. The initiation of a quality improvement project has contributed to an improvement in patient outcomes at our institution.

  • Ovarian cancer
  • Quality
  • Primary debulking surgery
  • Neoadjuvant chemotherapy
  • Preoperative algorithm

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  • The authors declare no conflicts of interest.