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Gynecologic Cancer InterGroup (GCIG) Consensus Review for Ovarian Small Cell Cancers
  1. Nicholas Simon Reed, MBBS*,
  2. Patricia Pautier, MD,
  3. Elizabeth Åvall-Lundqvist, MD,
  4. Chel-Hun Choi, MD§,
  5. Andreas du Bois, MD,
  6. Michael Friedlander, MBChB, FRACP, PhD,
  7. Anthony Fyles, MD#,
  8. Ganessan Kichenadasse, MD**,
  9. Diane M. Provencher, MD, and
  10. Isabelle Ray-Coquard, MD, PhD,
  1. *Beatson Oncology Centre, Glasgow, UK;
  2. Institut Gustave Roussy, Villejuif, France;
  3. Karolinska Intitute, Stockholm, Sweden;
  4. §Samsung Medical Centre, Sung Kyun Kwan University Medical Centre, Seoul, South Korea;
  5. University of Duisberg, Essen, Germany;
  6. National Health and Medical Research Council, Clinical Trials Centre, New South Wales, Australia;
  7. #Princess Margaret Hospital, Toronto, Canada;
  8. **Flinders Centre for Innovation in Cancer, South Australia, Australia;
  9. ††Centre hospitalier de l’Universite de Montreal, Montreal, Canada; and
  10. ‡‡Centre Leon Berard, Lyon, France.
  1. Address correspondence and reprint requests to Nicholas Simon Reed, MBBS, Beatson Oncology Centre, 1053 Great Western Road, Glasgow G12 0YN, Scotland, United Kingdom. E-mail: nick.reed{at}ggc.scot.nhs.uk.

Abstract

Abstract Small cell carcinomas of the ovary are uncommon and account for less than 1% of ovarian cancers. They were first recognized in 1979, and a number of reports appeared during the next 2 decades. They are highly aggressive tumors and usually carry a poor prognosis, although this may reflect that most are diagnosed at advanced stage; however, those diagnosed as stage 1A have only 30% to 40% of long-term survivors. More reports followed extending our experience in the diagnosis and management of these rare cancers. The classification is described below and shown in Table 1, but a revision is expected to be published from the World Health Organization in 2014.

  • Small cell carcinoma ovary
  • Surgery
  • Chemotherapy
  • Radiation therapy
  • Rare cancers
  • Hypercalcaemia
  • Pulmonary type

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Footnotes

  • The authors declare no conflicts of interest.

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