Article Text

Download PDFPDF
Is Routine Appendectomy at the Time of Primary Surgery for Mucinous Ovarian Neoplasms Beneficial?
  1. Tomer Feigenberg, MD*,
  2. Allan Covens, MD*,
  3. Zeina Ghorab, MD,
  4. Nadia Ismiil, MD,
  5. Valérie Dubé, MD,
  6. Reda S. Saad, MD,
  7. Mahmoud A. Khalifa, MD and
  8. Sharon Nofech-Mozes, MD
  1. *Division of Gynecologic Oncology, University of Toronto; Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; and
  2. Department of Anatomic Pathology, University of Toronto; Department of Pathology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
  1. Address correspondence and reprint requests to Sharon Nofech-Mozes, MD, Department of Pathology, Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Toronto, Ontario, Canada, M4N 3M5. E-mail: sharon.nofech-mozes{at}


Objectives To evaluate the value of an appendectomy at the time of surgery for ovarian mucinous borderline tumors or carcinoma.

Methods A retrospective single institute–based study was conducted. We identified patients who were operated on by a gynecologic oncologist for an abnormal pelvic mass, which was diagnosed as mucinous adenocarcinoma or mucinous borderline tumor between January 2000 and December 2010. Cases were included in the study if an appendectomy was performed at the time of initial surgery.

Results Seventy-seven cases meeting the inclusion criteria were identified. The ovarian mass of 11 patients (14%) was diagnosed as metastatic appendiceal carcinoma involving the ovary. Evidence of metastatic disease, abnormal-looking appendix, or pseudomyxoma peritonei, were identified at the time of surgery for all of these cases. The condition of 30 patients (39%) and 36 patients (47%) were diagnosed as mucinous borderline ovarian tumor and invasive or microinvasive mucinous ovarian carcinoma, respectively. Evidence of metastasis from the ovary to the appendix was not identified in any of the cases.

Conclusions Our data suggest that in cases of apparent early-stage mucinous ovarian borderline tumors and cancer, adding an appendectomy at the time of surgery is not warranted in the absence of a grossly abnormal appendix or evidence of metastatic disease.

  • Appendix
  • Ovarian tumors
  • Mucinous
  • Cancer
  • Borderline tumors

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • The authors declare no conflicts of interest.