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Vaginal Vault Dehiscence and Increased Use of Vaginal Vault Brachytherapy: What are the Implications?
  1. Ericka Wiebe, MD*,
  2. Allan Covens, MD and
  3. Gillian Thomas, MD, FRCPC, FRCR (Hon)*
  1. *Department of Radiation Oncology, and
  2. Department of Obstetrics and Gynecology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
  1. Address correspondence and reprint requests to Gillian Thomas, MD, Odette Cancer Centre, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5. E-mail:


Abstract Literature reports describe the potential for increased incidence of vaginal vault dehiscence after minimally invasive surgery, and incidental reports of vaginal vault dehiscence with vaginal vault brachytherapy. This review explores the risk of increased vaginal complications in a setting of greater use of both minimally invasive surgical techniques and adjuvant vaginal vault brachytherapy in early endometrial cancer. The impact of associated patient-related and tumor-related risk factors on clinical decision making is evaluated in selecting therapy that provides optimal tumor control while minimizing treatment adverse effects.

  • Uterine carcinoma
  • Vaginal complications
  • Brachytherapy

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  • The authors did not receive support for this work.

  • The authors declare no conflicts of interest.

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