Trop-2 Overexpression in Poorly Differentiated Endometrial Endometrioid Carcinoma: Implications for Immunotherapy With hRS7, a Humanized Anti–Trop-2 Monoclonal Antibody

Eliana Bignotti; Antonella Ravaggi; Chiara Romani; Marcella Falchetti; Silvia Lonardi; Fabio Facchetti; Sergio Pecorelli; Joyce Varughese; Emiliano Cocco; Stefania Bellone; Peter E. Schwartz; Thomas J. Rutherford; Alessandro D. Santin

doi:10.1097/IGC.0b013e318228f6da

Article info

Uterine Cancer

Trop-2 Overexpression in Poorly Differentiated Endometrial Endometrioid Carcinoma: Implications for Immunotherapy With hRS7, a Humanized Anti–Trop-2 Monoclonal Antibody

Authors

Eliana Bignotti Angelo Nocivelli Institute of Molecular Medicine, Division of Gynecologic Oncology and PubMed articles Google scholar articles
Antonella Ravaggi Angelo Nocivelli Institute of Molecular Medicine, Division of Gynecologic Oncology and PubMed articles Google scholar articles
Chiara Romani Angelo Nocivelli Institute of Molecular Medicine, Division of Gynecologic Oncology and PubMed articles Google scholar articles
Marcella Falchetti Department of Pathology, University of Brescia, Brescia, Italy; and PubMed articles Google scholar articles
Silvia Lonardi Department of Pathology, University of Brescia, Brescia, Italy; and PubMed articles Google scholar articles
Fabio Facchetti Department of Pathology, University of Brescia, Brescia, Italy; and PubMed articles Google scholar articles
Sergio Pecorelli Angelo Nocivelli Institute of Molecular Medicine, Division of Gynecologic Oncology and PubMed articles Google scholar articles
Joyce Varughese Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT. PubMed articles Google scholar articles
Emiliano Cocco Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT. PubMed articles Google scholar articles
Stefania Bellone Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT. PubMed articles Google scholar articles
Peter E. Schwartz Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT. PubMed articles Google scholar articles
Thomas J. Rutherford Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT. PubMed articles Google scholar articles
Alessandro D. Santin Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT. PubMed articles Google scholar articles

Address correspondence and reprint requests to Alessandro D. Santin, MD, Department of Obstetrics, Gynecology & Reproductive Sciences, Room 305 LSOG, Yale University School of Medicine, 333 Cedar St, PO Box 208063, New Haven, CT 06520-8063. E-mail: alessandro.santin{at}yale.edu.

Citation

Bignotti E, Ravaggi A, Romani C, et al

Trop-2 Overexpression in Poorly Differentiated Endometrial Endometrioid Carcinoma: Implications for Immunotherapy With hRS7, a Humanized Anti–Trop-2 Monoclonal Antibody

International Journal of Gynecologic Cancer 2011;21:1613-1621.

Publication history

Received April 11, 2011
Accepted June 13, 2011
First published November 1, 2011.

Online issue publication

June 17, 2019

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