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Polypropylene Mesh Implantation in Combination With Vacuum-Assisted Closure in the Management of Metastatic or Locally Recurrent Vulvar Cancer: Case Report and Review of Literature
  1. Erik Riebe, MD,
  2. Ralf Ohlinger, MD,
  3. Franziska Thele, MD and
  4. Günter Köhler
  1. Department of Gynecology and Obstetrics, Ernst-Moritz-Arndt University Greifswald, Greifswald, Germany.
  1. Address correspondence and reprint requests to Erik Riebe, MD, Department of Gynecology and Obstetrics, Ernst-Moritz-Arndt University Greifswald, Greifswald 17475, Wollweberstraße 1-3. E-mail: erik.riebe{at}


Background: Mesh reconstruction, especially in combination with vacuum-assisted closure, might improve healing and reduce the surgical morbidity of extensive inguinofemoral lymphadenectomy or extensive local resection in progressive cancer of the vulva.

Cases: Radical vulvectomy combined with inguinofemoral lymphadenectomy was performed in 2 patients (P1, P2). The inguinofemoral wound bed was stabilized by polypropylene mesh implantation and sealed with vacuum closure system. In 1 patient with local recurrence of vulvar cancer (P3), local excision and stabilization of the wound were performed by mesh implantation.

Conclusions: Mesh implantation fulfills 2 purposes: (1) it protects exposed vessels and the wound can be vacuum sealed; and (2) it stabilizes the surgical bed, permitting the required radical excision locally and inside the vascular compartment.

  • Vulvar cancer
  • Vacuum-assisted closure
  • Mesh implantation
  • Inguinofemoral lymphadenectomy

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