Article Text

Download PDFPDF
Resolution of pulmonary metastases with chemotherapy in a patient with placental site trophoblastic tumor
  1. L. A. KING*,
  2. T. OKAGAKI*, and
  3. L. B. TWIGGS*
  1. *Women's Cancer Center, Department of Obstetrics and Gynecology
  2. Department of Laboratory Medicine, University of Minnesota Health Science Center, Minneapolis, Minnesota 55455, USA
  1. Address for correspondence: Laurel A. King, MD, CK-166, Department of Obstetrics and Gynecology, Medical College of Georgia, Augusta, Georgia 30912, USA.


Placental site trophoblastic tumor (PSTT), a rare variant of gestational trophoblastic disease, was first described in 1976. PSTT is usually seen in young women, generally treated by hysterectomy, and is associated with a 20% fatality rate. The development of metastases secondary to PSTT is associated with an extremely poor prognosis. Metastatic PSTT has generally been resistant to chemotherapy although one complete and some partial responses have been noted previously. We report a case of a complete chemotherapeutic response in a patient with pulmonary metastases.

  • beta hCG
  • multi-agent chemotherapy
  • placental site trophoblastic tumor (PSTT)
  • trophoblastic disease

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.