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Epithelial ovarian tumors of borderline malignancy: a study of 50 cases
  1. B. Piura*,
  2. R. Dgani§,
  3. I. Blickstein§,
  4. I. Yanai-Inbar,
  5. B. Czernobilsky and
  6. M. Glezerman
  1. * The Unit of Gynecologic Oncology,
  2. Division of Obstetrics and Gynecology and
  3. the Department of Pathology, Soroka Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel;
  4. § The Department of Obstetrics and Gynecology, and
  5. The Department of Pathology, Kaplan Hospital, Rehovot, Israel
  1. Address for correspondence: Dr B. Piura, MDMRCOG, Head of Gynecologic Oncology Unit, Division of Obstetrics and Gynecology, Soroka Medical Center, PO Box 151, Beer-Sheva 84101, Israel.


Of 50 patients with borderline epithelial ovarian tumors, 32 (64%) had serous, 17 (34%) had mucinous and one (2%) had endometrioid tumor. All patients with mucinous tumor had stage I disease, whereas 4 patients with serous tumor had stage II–III disease. Five patients (10%) were pregnant at the time of diagnosis. Seventeen patients (34%) had initial surgery with ovarian conservation and 7 of them were not subjected to further surgery. Five patients (10%) received adjuvant chemotherapy. Five-year survival and 5-year disease-free survival rates were 100% and 96.4%, respectively. It is concluded that for patients with stage IA disease unilateral salpingo-oophorectomy seems to be adequate treatment and for those with more than stage IA disease, surgery should include total abdominal hysterectomy and bilateral salpingo-oophorectomy. Although the effectiveness of chemotherapy in these tumors is uncertain, adjuvant chemotherapy is advocated for patients in whom spread of the tumor beyond the ovaries has occurred.

  • adjuvant chemotherapy
  • borderline malignancy
  • conservative surgery
  • epithelial ovarian tumors
  • low malignancy potential.

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