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Cervical Carcinoma: Postoperative Radiotherapy: Fifteen-Year Experience in a Norwegian Health Region
  1. Elke Lorenz, MD*,
  2. Trond Strickert, MSc and
  3. Bjørn Hagen, MD, PhD*
  1. * Departments of Gynaecological Oncology and
  2. Oncology and Radiotherapy, St Olavs Hospital, University Hospital, Trondheim, Norway.
  1. Address correspondence and reprint requests to Elke Lorenz, MD, Department of Obstetrics and Gynaecology, St Olavs Hospital, University Hospital, N 7006 Trondheim, Norway. E-mail: el-loren{at}


Introduction: To study the results in cervical carcinoma after a combined treatment with surgery and radiotherapy with regard to survival and side effects.

Methods: A retrospective analysis of 71 patients who underwent radical hysterectomy and postoperative radiotherapy between January 1, 1987, and December 31, 2001, was performed.

Results: Median follow-up periods were 162 months for surviving patients and 62 months for deceased patients. The 5-year overall survival and disease-specific survival for all stages were 80.3% and 82.7%, respectively. The 5-year actuarial incidence of late reactions for grade 1 + 2 was as follows: for upper gastrointestinal tract, 36%; for rectum, 37%; for urinary tract, 19%; for vagina, 26%; and for lymph edema, 19%. The 5-year actuarial incidence of late reactions for grade 3 + 4 was as follows: for upper gastrointestinal tract, 12%; and for rectum, 3%.

Conclusions: Careful pretreatment workup and well-defined criteria for postoperative radiotherapy are essential, and new treatment options such as intensity-modulated radiation therapy should be considered.

  • Cervical carcinoma
  • Postoperative radiotherapy
  • Survival
  • Side effects

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