Article Text

Download PDFPDF
Early Cervical Cancer Managed by Laparoscopy and Conventional Surgery: Comparison of Treatment Results
  1. Piotr Sobiczewski, MD, PhD*,
  2. Mariusz Bidzinski, MD, PhD*,
  3. Pawel Derlatka, MD, PhD*,
  4. Grzegorz Panek, MD, PhD*,
  5. Anna Danska-Bidzinska, MD, PhD*,
  6. Leszek Gmyrek, MD* and
  7. Wojciech Michalski
  1. *Gynecologic Oncology Department and
  2. Biostatistic Department, the Maria Sklodowska-Curie Memorial Cancer Center, Warsaw, Poland.
  1. Address correspondence and reprint requests to Piotr Sobiczewski, MD, PhD, Gynecologic Oncology Department, the Maria Sklodowska-Curie Memorial Cancer Center, Roentgena 5, 02-781 Warsaw, Poland. E-mail: sobiczewskipiotr{at}


Introduction: The goal of this retrospective analysis was to compare the results of treatment in patients with early cervical cancer managed by laparoscopy with those for patients observed after laparotomy.

Methods: The retrospective analysis was carried out with 22 patients operated on with total laparoscopic hysterectomy and 58 patients treated by abdominal hysterectomy. Patients with clinical tumor stage IA, IB1, or IIA were eligible for surgery. The main efficacy end point was disease-free survival evaluated by the Kaplan-Meier method. The survival curves were compared using log-rank tests. In addition, length of hospitalization, duration of surgery, and complication rate were compared. P < 0.05 was set as statistically significant.

Results: Predicted 3-year disease-free survival rates in the "open surgery" and "laparoscopy" groups were 0.86 (standard deviation [SD], 0.049) and 0.82 (SD, 0.098), respectively (P = 0.53). Recurrence rate was 13.6% after laparoscopy and 12% in open surgery. In 2 patients, intraperitoneal spread occurred after laparoscopy. The operation time was longer and hospitalization shorter after laparoscopy.

Conclusions: The 3-year disease-free survival was similar in both groups. Total laparoscopic radical hysterectomy may be an option in early cervical cancer; however, the intraperitoneal spread in 2 patients compels a search for possible risk factors in patients managed by laparoscopy.

  • Cervical cancer
  • Laparoscopy
  • Laparotomy

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.