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Accuracy of Ultrasonography With Color Doppler in Ovarian Tumor: A Systematic Quantitative Review
  1. Lidia Rosi Medeiros, MD, MSc*,
  2. Daniela Dornelles Rosa, MD, PhD,,
  3. Maria Inês Da Rosa, MD, PhD*,§ and
  4. Mary Clarisse Bozzetti, MD, PhD*,
  1. *Postgraduate Program in Epidemiology at Federal University of Rio Grande do Sul;
  2. Hospital Fêmina and Hospital Moinhos deVento;
  3. Postgraduate Program in Medicine: Medical Sciences at Federal University of Rio Grande do Sul, Porto Alegre;
  4. §Medical School at University of Extremo Sul Catarinense, Criciúma;
  5. Department of Social Medicine, Faculty of Medicine at Federal University of Rio Grande do Sul, Porto Alegre Brazil.
  1. Address correspondence and reprint requests to Lidia Rosi Medeiros, MD, MSc, José de Alencar 1244 apt 1009, Porto Alegre, RS, Brazil, CEP 90880-480. E-mail: lidia.rosi{at}


A quantitative systematic review was performed to estimate the accuracy ultrasonography with color Doppler in the diagnosis of ovarian tumors. Studies that compared color Doppler ultrasonography with paraffin-embedded sections parameters for the diagnosis of ovarian tumors were included. Twelve studies were analyzed, which included 2398 women. The pooled sensitivity was 0.87 (95% confidence interval [CI] 0.84-0.90); and the specificity was 0.92 (95%CI, 0.87-0.90). The diagnostic odds ratio for ovarian cancer and borderline lesions versus benign lesions was 125 (95%CI, 55-283). Summary receiver operating characteristic curves were constructed because of heterogeneity in the diagnostic odds ratio. For malignant ovarian cancer and borderline versus benign lesions the area under the curve was 0.9577. In conclusion, ultrasonography with color Doppler is a useful preoperative test for predicting the diagnosis of pelvic masses.

  • Ultrasonography
  • Color Doppler
  • Ovarian tumor
  • Systematic review
  • Metaanalysis
  • Accuracy
  • Diagnosis

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  • Contributors: LRM had full access to all data and took responsibility for the integrity and the accuracy of the analysis. DDR, MIR and MCB organized the study concept and the design. LRM acquired, analyzed and interpreted the data. LRM, DDR, MIR and MCB drafted the manuscript. LRM and DDR performed the statistical analysis.

  • The authors declare no conflict of interest.