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  • Adnexal Mass Vascularity Assessed by 3-Dimensional Power Doppler: Does It Add to the Risk of Malignancy Index in Prediction of Ovarian Malignancy?: Four Hundred-Case Study

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Ovarian Cancer
Adnexal Mass Vascularity Assessed by 3-Dimensional Power Doppler: Does It Add to the Risk of Malignancy Index in Prediction of Ovarian Malignancy?: Four Hundred-Case Study
  1. Ghada M. Mansour, MD*,
  2. Ismail K. El-Lamie, MD*,
  3. Helmy M. El-Sayed, MD*,
  4. A. M. Ibrahim, MD*,
  5. M. Laban, MD*,
  6. Sobhi K. Abou-Louz, MD*,
  7. M. Y. Abd Allah, MD*,
  8. M. N. El-Mahallawi, MD*,
  9. Khalil I. El-Lamie, MD* and
  10. Mohsen Gad-Allah, MD†
  1. *Departments of Obstetrics and Gynecology, and
  2. †Departments of Community Medicine, Ain Shams University, Cairo, Egypt.
  1. Address correspondence and reprint requests to Ghada M. Mansour, MD, Ain Shams University, 5th El-Gahez St, 7th Area, Nasr City, Cairo, Egypt. E-mail: gmansour{at}hotmail.com; dodimansour{at}gmail.com.

Abstract

The Risk of Malignancy Index (RMI) is used for the prediction of ovarian malignancy. It includes menopausal status, carbohydrate antigen 125 serum levels, and ultrasound criteria. Three-dimensional power Doppler (3-DPD) is a reproducible investigation for assessment of tumor vascularity, classifying vascularity to avascular, parallel, and chaotic patterns. In this study; 3-DPD was added to RMI for prediction of malignancy in 400 cases of ovarian masses. Sensitivity of RMI for prediction of malignancy was 88%, with a cutoff value of 202.5 at 95% confidence interval. Sensitivity of 3-DPD for prediction of malignancy was 75%, adding 3-DPD to RMI increased its sensitivity to 99%. Considering the pilot nature of the study, further studies are needed to corroborate such findings.

  • Ovarian malignancy
  • Risk of Malignancy Index
  • 3-Dimensional power Doppler ultrasound
  • CA-125

http://dx.doi.org/10.1111/IGC.0b013e3181a8335e

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