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Promising Effect of Aromatase Inhibitors on Recurrent Granulosa Cell Tumors
  1. Jacob Korach, MD*,
  2. Tamar Perri, MD*,
  3. Mario Beiner, MD*,
  4. Tima Davidzon, MD,
  5. Eddie Fridman, MD and
  6. Gilad Ben-Baruch, MD*
  1. *Departments of Gynecologic Oncology,
  2. Departments of Nuclear Medicine, and
  3. Departments of Pathology, Sheba Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel.
  1. Address correspondence and reprint requests to Jacob Korach, MD, Department of Gynecologic Oncology, Sheba Medical Center, 52621 Tel HaShomer, Israel. E-mail: jacobkorach{at}


Recurring adult-type granulosa cell tumors of the ovary are usually treated by surgical resection followed by chemotherapy or radiation. However, the results of such treatment are disappointing. We describe 4 patients in whom recurrent ovarian granulosa cell tumors were treated with an aromatase inhibitor, with promising results.

  • Granulosa cell tumor
  • Recurrent
  • Aromatase inhibitor

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