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First case of vaginal radical trachelectomy in a pregnant patient
  1. H. P. Van De Nieuwenhof,
  2. M. A.P.C. Van Ham,
  3. F. K. Lotgering and
  4. L. F.A.G. Massuger
  1. Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
  1. Address correspondence and reprint requests to: Hedwig van de Nieuwenhof, MD, Department of Obstetrics and Gynaecology (791), Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands. Email: h.nieuwenhof{at}


Women who present with cervical carcinoma during pregnancy pose for us a clinical problem. In general, three treatment options exist: (i) radical hysterectomy with termination of pregnancy, (ii) a planned delay, or (iii) chemotherapy until lung maturation has occurred, both followed by a radical hysterectomy. Vaginal radical trachelectomy is an alternative approach to preserve the pregnancy. We report on a woman with a stage IBI cervical carcinoma, diagnosed at 16 weeks of gestation treated with vaginal radical trachelectomy. At a gestational age of 36 weeks, a cesarean section was performed, followed by radical hysterectomy. Follow-up of 9 months is uneventful for both the mother and the child. The vaginal radical trachelectomy is a new approach in the treatment of cervical carcinoma during pregnancy.

  • cervical carcinoma
  • pregnancy
  • trachelectomy

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