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Treatment of aggressive angiomyxoma with aromatase inhibitor prior to surgical resection
  1. D. L. Giles*,
  2. P. T. Liu,
  3. T. K. Lidner and
  4. P. M. Magtibay*
  1. * Departments of Gynecologic Surgery,
  2. Radiology, and
  3. Pathology, Mayo Clinic, Scottsdale, Arizona
  1. Address correspondence and reprint requests to: Dobie L. Giles, MD, Mayo Clinic, Department of Gynecologic Surgery, 5779 East Mayo Blvd., Phoenix, Arizona 85054. Email: giles.dobie{at}


Aggressive angiomyxoma (AA) is a rare, locally infiltrating soft tissue tumor typically located in the genital tract of young, reproductive age women. Surgical excision has been the mainstay of treatment. Recently, gonadotropin-releasing hormone agonist therapy has been reported to decrease the size of estrogen-receptor positive AA. We present the first case of a postmenopausal woman treated with an aromatase inhibitor to shrink the size of tumor prior to surgical resection.

  • angiomyxoma
  • aromatase inhibitor
  • estrogen receptor

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