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Multimodal therapy for the initial management of genital embryonal rhabdomyosarcoma in childhood
  1. N. R. Maharaj*,
  2. D. Nimako* and
  3. G. P. Hadley
  1. *Departments of Obstetrics and Gynaecology and
  2. Departments of Paediatric Surgery, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa
  1. Address correspondence and reprint requests to: Niren Ray Maharaj, FCOG(SA), MMed(O&G), Department of Obstetrics and Gynaecology, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Private Bag 7, Congella, Durban 4013, South Africa. Email: maharajn13{at}


Rhabdomyosarcoma is the most common soft tissue sarcoma found in children. A polypoid form of the embryonal type of rhabdomyosarcoma, namely, sarcoma botryoides, is often found in girls younger than 5 years, and typically presents as a polypoid mass protruding from the vagina. Over the years, there has been a shift in the treatment of this condition from radical surgery to a multimodal approach involving conservative surgery with chemotherapy and radiotherapy. This approach has been associated with improved survival and preservation of normal anatomy and function. We discuss the initial management of a 4-year-old girl with pelvic embryonal rhabdomyosarcoma using a multimodal approach.

  • embryonal rhabdomyosarcoma
  • multimodal therapy

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