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Adjuvant therapy for early-stage endometrial cancer: a review
  1. S. Tangjitgamol*,
  2. S. Manusirivithaya* and
  3. C. Lertbutsayanukul
  1. * Gynecologic Oncology Unit, Department of Obstetrics and Gynecology, Bangkok Metropolitan Administration Medical College and Vajira Hospital, Bangkok, Thailand; and
  2. Division of Radiation Oncology, Department of Radiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
  1. Address correspondence and reprint requests to: Siriwan Tangjitgamol, MD, Gynecologic Oncology Unit, Department of Obstetrics and Gynecology, Bangkok Metropolitan Administration Medical College and Vajira Hospital, 681 Samsen Road, Dusit District, Bangkok 10300, Thailand. Email: siriwanonco{at}yahoo.com

Abstract

Most patients with endometrial cancer (EMC) present their symptoms early in their course, leading to an overall favorable outcome. However, some patients who are in early-stage diseases may carry some risk features that would hamper their prognoses. For these early-stage diseases with high risk of recurrences, radiation therapy certainly plays a major role as an adjuvant treatment. Despite an excellent local diseases control by radiation, systemic failures are still encountered. To improve the prognoses, other types of adjuvant therapy have been attempted. In this review, various options of adjuvant treatment for this early-stage EMC including radiation therapy, chemotherapy, and hormonal therapy are discussed.

  • adjuvant treatment
  • early stage
  • endometrial cancer

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