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Ovarian cancer associated with carcinomatous meningitis: a case report and review of the literature
  1. L. Decelle*,
  2. L. D'HONDT*,
  3. M. Andre*,
  4. P. Delree,
  5. B. Calicis,
  6. C. Lonchay*,
  7. C. Ide§ and
  8. J.-L. Canon*
  1. * Department of Hematology/Oncology, Centre Hospitalier Notre-Dame et Reine Fabiola, Charleroi, Belgium;
  2. Institut de Pathologie et de Génétique, Gosselies, Belgium; and Departments of
  3. Surgery and
  4. § Radiology, Centre Hospitalier Notre-Dame et Reine Fabiola, Charleroi, Belgium
  1. Address correspondence and reprint requests to: Lionel D'Hondt, MD, PhD, Department of Hematology/Oncology, Centre Hospitalier Notre-Dame et Reine Fabiola, Grand'Rue 3, 6000 Charleroi, Belgium. Email: dhondt.lionel{at}chndrf.be

Abstract

We report the case of a 62-year-old patient who developed a carcinomatous meningitis while on second-line chemotherapy for ovarian cancer. Cytologic analyses confirmed that carcinomatous cells of ovarian origin were present in cerebrospinal fluid. Carcinomatous meningitis is a very rare event in the natural history of ovarian carcinoma. We discuss the specificity of our case in the light of the literature. In addition, we present some relevant radiologic and pathologic documents illustrating this rare entity.

  • carcinomatous meningitis
  • chemotherapy
  • ovarian cancer

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