Article Text

Download PDFPDF
F-18 fluorodeoxyglucose uptake in leiomyomatous uterus
  1. M. Shida*,
  2. M. Murakami*,
  3. H. Tsukada*,
  4. Y. Ishiguro*,
  5. K. Kikuchi*,
  6. E. Yamashita,
  7. H. Kajiwara,
  8. M. Yasuda and
  9. M. Ide§
  1. * Departments of Obstetrics & Gynecology, Tokai University School of Medicine, Kanagawa, Japan
  2. Departments of Radiology, Tokai University School of Medicine, Kanagawa, Japan
  3. Departments of Pathology, Tokai University School of Medicine, Kanagawa, Japan
  4. § HIMEDIC Imaging Center, Lake Yamanaka, Yamanashi, Japan
  1. Address correspondence and reprint requests to: Masaru Murakami, MD, PhD, Department of Obstetrics and Gynecology, Tokai University Oiso Hospital, Tokai University School of Medicine, Oiso Town, Kanagawa 259-0198, Japan. Email: masarumu{at}


Leiomyomas of uterus are common disease in gynecology. It is important to differentiate leiomyoma from leiomyosarcoma at the decision of treatment methods, especially in the case of the conservative treatment for uterine leiomyoma. But the exact diagnosis of benign leiomyoma is often difficult due to the degeneration of myoma by imaging modalities including magnetic resonance imaging. Recently, whole-body positron emission tomography (PET) using F-18 fluorodeoxyglucose (FDG) has been used for a diagnosis of malignant tumors. There is a growing body of evidence for the use of FDG in differentiating malignant from benign disease. But optimal utilization in gynecology remains unclear. Our case represents increased uptake of FDG in myomatous uterus, which is pathologically confirmed benign leiomyoma by the hysterectomy. Immunohistochemical analysis of glucose transporter-1 showed positive in endometrial tissue and negative in leiomyoma. Our case indicates that myomatous uterus in premenopausal women shows the potential pitfall of a positive result of FDG-PET

  • uterine leiomyoma

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.