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Uterine tumor resembling ovarian sex cord tumors in a patient using tamoxifen: report of a case and review of literature
  1. O. Oztekin*,
  2. F. Soylu*,
  3. S. Yigit and
  4. E. Sarica*
  1. *2nd Obstetrics and Gynecology Clinic, Department of Gynecologic Oncology, Ataturk Education and Training Hospital, Izmir, Turkey
  2. Pathology Clinic, Ataturk Education and Training Hospital, Izmir, Turkey
  1. Address correspondence and reprint requests to: Ozer Oztekin, MD, 170 Sok No. 23/4 Basin Sitesi, 35360, Izmir, Turkey. Email: ozeroztekin{at}


Increasing number of uterine malignancies have been reported in breast cancer patients using tamoxifen. Most of these are endometrial adenocarcinomas. However, only a few cases of endometrial stromal sarcomas have been reported to be linked with tamoxifen usage. A 58-year-old postmenopausal women who had been using tamoxifen for 4 years after a surgery for breast cancer is presented with chronic pelvic pain. Preoperative investigations were indicative of a uterine myoma so that a standard total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed. Postoperative histologic diagnosis was a uterine tumor resembling ovarian sex cord tumors, which is an exceedingly rare entity itself. The present case is the first designated diagnosis of this rare tumor, with a possible association of tamoxifen usage.

  • endometrial stromal tumor
  • tamoxifen
  • uterine tumor resembling ovarian sex cord tumors

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