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Correspondence and Brief Reports
Integrated 18F‐fluorodeoxyglucose positron emission tomography and computerized tomography in endodermal sinus tumor
  1. C. Klieger*,
  2. R. Dvir†,
  3. E. Even-Sapir‡,
  4. J. B. Lessing*,
  5. Y. Burstein† and
  6. D. Grisaru*
  1. *Department of Obstetrics and Gynecology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
  2. †Department of Pediatric Oncology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
  3. ‡Department of Nuclear Medicine, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
  1. Address correspondence and reprint requests to: Dan Grisaru, MD, PhD, Gynecologic Oncology Service, Tel Aviv Sourasky Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel. Email: grisaro{at}post.tau.ac.il

Abstract

Application of an in-line positron emission tomography and computerized tomography (PET-CT) in endodermal sinus tumor (EST) is described in this study. Case 1: A young female with massive ascites postovarian mass resection had elevated alpha-fetoprotein (AFP) serum levels. Following a positive PET–CT study with increased 18F-fluorodeoxyglucose (FDG) uptake, a CT-guided core biopsy of a peritoneal mass was performed. EST was diagnosed histologically. The patient was disease free after chemotherapy. Follow-up PET–CT was negative in keeping with no viable tumor tissue. Case 2: A large pelvic mass diagnosed histologically as primarily EST was removed in a teenage patient with elevated AFP levels. PET-CT showed diffuse abdominal spread of FDG uptake, suggesting extensive peritoneal seeding. The patient was disease free after chemotherapy. Follow-up PET-CT was negative. EST is an FDG-avid tumor. PET–CT delineated the prechemotherapy tumor extent adequately ruled out the presence of residual tumor after a successful treatment.

  • endodermal sinus tumor
  • PET–CT
  • residual tumor

https://doi.org/10.1136/ijgc-00009577-200607000-00030

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