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The pathology and management of endocervical glandular neoplasia
  1. A. A. El-GHOBASHY*,
  2. A. M. Shaaban,
  3. J. Herod and
  4. C. S. Herrington§
  1. * Department of Obstetrics and Gynaecology, Bradford Royal Infirmary, Bradford, West Yorkshire, United Kingdom
  2. Department of Pathology, St. James's Hospital, Leeds, United Kingdom
  3. Department of Obstetrics and Gynaecology, Liverpool Women's Hospital, Liverpool, United Kingdom
  4. § Bute Medical School, University of St. Andrews, St. Andrews, United Kingdom
  1. Address correspondence and reprint requests to: Professor C. Simon Herrington, DPhil, FRCP, FRCPath, Professor of Pathology, University of St Andrews, Bute Medical School, Westburn Lane, St Andrews, FIFE, KY16 9TS, UK. Email: csh2{at}


The incidence of cervical glandular intraepithelial neoplasia and adenocarcinoma is rising, and our limited knowledge about these lesions presents the gynecologist with a management dilemma. Recently, pathologists have paid increasing attention to the diagnosis and pathogenesis of adenocarcinoma of the cervix. Although there is no uniformity in the management of these lesions, nonradical surgery appears to give satisfactory results especially in young women who want to preserve their fertility. This review focuses on the issues surrounding the histologic diagnosis of endocervical glandular abnormalities, including their classification, and discusses the management of cervical preinvasive glandular disease, including follow-up after treatment

  • cervical
  • glandular
  • pathology
  • treatment

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