Article Text

Download PDFPDF
Vaginal malignant melanoma: a case report and literature review
  1. M. Moodley*,
  2. M. Daya and
  3. J. Moodley*
  1. * Gynecology-Oncology Unit, NR Mandela School of Medicine, Durban, South Africa
  2. Department of Plastic & Reconstructive Surgery, NR Mandela School of Medicine, Durban, South Africa
  1. Address correspondence and reprint requests to: Dr M. Moodley, Gynecology-Oncology Unit, Department Obstetrics & Gynecology, NR Mandela School of Medicine, University of Natal, 719 Umbilo Road, Durban, 4001 KwaZulu-Natal, South Africa. Email: moodleym29{at}


Vaginal melanomas are rare genital malignancies occurring mainly in the 6th and 7th decades of life. In general, they have a worse prognosis than cutaneous melanomas. In the past, various treatment modalities have been recommended including radical pelvic surgery. However, the prognosis is poor in spite of such radical approaches. More recently, more conservative treatment in the form of wide local excision combined with adjuvant chemotherapy, high-dose radiotherapy, and immunotherapy seem to have promising results. We describe a patient with vaginal malignant melanoma treated with conservative local excision as well as adjuvant radiotherapy, chemotherapy, and interferon.

  • vaginal melanoma
  • interferon
  • radiotherapy
  • surgery

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.