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Synchronous mucinous adenocarcinoma of the endometrium and mucinous cystadenoma of bilateral ovaries presenting during fertility therapy
  1. T. Gotoh*,
  2. N. Hayashi*,
  3. S. Takeda*,
  4. S. Itoyama,
  5. M. Takano and
  6. Y. Kikuchi
  1. * Department of Obstetrics and Gynecology, National Defense Medical College, Saitama, Japan
  2. Department of Laboratory Medicine, Saitama Medical Center, National Defense Medical College, Saitama, Japan
  3. Department of Obstetrics and Gynecology, National Defense Medical College, Saitama, Japan
  1. Address correspondence and reprint requests to: Tomoko Gotoh, Department of Obstetrics and Gynecology, Saitama Medical Center, Kamoda 1981, Kawagoe, Saitama 350–8550, Japan. Email: tomochan{at}


We describe a very rare case of synchronous mucinous tumor of the endometrium and ovaries presenting during ovulation induction. A 31-year-old woman received ovulation induction for 5-year primary infertility. Ultrasonography revealed mucus retention in the uterine cavity and bilateral multicystic ovaries during ovulation induction. Atypical hyperplasia was diagnosed by endometrial curettage. Repeated procedures including ovarian cystectomy, endometrial curettage and in vitro fertilization combined with progestine therapy resulted in no pregnancy but rapid recurrences. She finally underwent simple hysterectomy and bilateral salpingo-oophorectomy. Microscopic examination revealed mucinous cystadenoma in the both ovaries and well differentiated mucinous adenocarcinoma of the endometrium.

  • fertility therapy
  • mucinous adenocarcinoma
  • synchronous tumor

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