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Benign mixed tumor of the vagina: Case report with expanded immunohistochemical profile
  1. F. Murdoch*,
  2. R. Sharma and
  3. A. Al-Nafussi
  1. * Department of Pathology, Stirling Royal Infirmary, Edinburgh, Scotland, UK
  2. Department of Obstetrics and Gynaecology, Falkirk District Royal Infirmary, Edinburgh, Scotland, UK
  3. Department of Pathology, University of Edinburgh, Edinburgh, Scotland, UK
  1. Address correspondence and reprint requests to: Dr Awatif Al-Nafussi, Department of Pathology, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK. Email: a.alnafussi{at}ed.ac.uk

Abstract

We present a case of benign mixed tumor of the vagina with its typical clinicopathologic and expanded immunohistochemical features. The strong coexpression of the mesenchymal spindle cell component with epithelial markers such as CK7, together with strong CD10, Bcl2, and estrogen and progesterone receptors favors a mullerian derived tumor. The tumor is best labeled as benign mixed mullerian tumor as originally designated.

  • mixed mullerian tumor
  • mixed tumor
  • spindle cell epithelioma
  • vagina

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