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Cervical implant from villoglandular endometrial adenocarcinoma masquerading as cervical villoglandular adenocarcinoma
  1. A Al-Nafussi1,
  2. J Obafunwa2,
  3. L. B Jordan1,
  4. I Fulton3,
  5. C Martin3 and
  6. G Beattie4
  1. 1 Department of Pathology, University of Edinburgh, Edinburgh;
  2. 2 Department of Pathology, King Edward VII Memorial Hospital, Hamilton, Bermuda;
  3. 3 Department of Obstetrics and Gynaecology, Royal Infirmary of Edinburgh, Edinburgh;
  4. 4 Obstetric and Gynaecology Department, St John's Hospital, West Lothian, United Kingdom

Abstract

Abstract. Al-Nafussi A, Obafunwa J, Jordan LB, Fulton I, Martin C, Beattie G. Cervical implant from villoglandular endometrial adenocarcinoma masquerading as cervical villoglandular adenocarcinoma.

This is an unusual presentation of a rare subtype of endometrial adenocarcinoma (villoglandular papillary carcinoma, VGPC) in a 71-year-old woman, which was initially diagnosed on cervical biopsy as being primary cervical VGPC. Loop excision failed to show any evidence of residual disease. Subsequent hysterectomy revealed a localized villoglandular carcinoma involving the uterine fundus and invading the inner one-third of the myometrium, the background endometrium was atrophic. The remaining cervix contained a focus of papillary forming endometrial type adenocarcinoma involving the surface epithelium and the superficial subepithelial glands. In conclusion, VGPC of cervix occurs mainly in young women and can be treated conservatively, pathologists should be cautious in making such a diagnosis in a postmenopausal woman before ruling out a primary endometrial origin.

  • cervix
  • uterus
  • villoglandular adenocarcinoma

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