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Invasive adenocarcinoma of the vagina following surgery for adenocarcinoma in situ of the cervix—Recurrence or implantation?
  1. G. V. Narayansingh,
  2. G. P. Cumming,
  3. S. Dighe,
  4. D. E. Parkin and
  5. Iain Millar
  1. From the Department of Obstetrics and Gynaecology, Aberdeen Royal Infirmary, Foresterhill, Scotland
  1. Address correspondence and reprint requests to: Gordon Narayansingh, 4 Rust Street, St. Clair, Port of Spain, TRINIDAD. E-mail: gordonvn{at}


A 51-year-old woman underwent cervical conization for severe glandular abnormal cells. Histology noted adenocarcinoma in situ (AIS) with incomplete excision margins. Four months later, hysterectomy revealed no residual disease. Six months subsequently she developed invasive adenocarcinoma of the upper vagina. This report documents the unusual behavior of AIS and its management difficulties.

  • cervical adenocarcinoma in situ
  • invasive vaginal occurrence

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