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Paraneoplastic cerebellar degeneration heralding fallopian tube adenocarcinoma
  1. R. Levite1,
  2. A. Fishman2,
  3. A. Kesler1,
  4. M. Altaras2 and
  5. N. Gadoth1
  1. 1Departments of Neurology &
  2. 2Gynecologic-Oncology Unit, Sapir Medical Center – Meir General Hospital, Kfar-Saba, and the Sackler Faculty of Medicine, Tel Aviv University, Israel
  1. Address correspondence and reprint requests to: Ami Fishman, MD, Gynecologic-Oncology Unit, Meir Hospital – Sapir Medical Center, Kfar-Saba, Israel 44281. Email: fishm{at}


The objective of this paper is to describe an 81-year-old woman with subacute cerebellar degeneration due to fallopian tube adenocarcinoma. Serum anti-Yo antibodies were used to screen for pelvic malignancy. Their presence led to a meticulous search, which included bilateral salpingoophorectomy. Subsequently an occult fallopian tube adenocarcinoma was discovered. This case report highlights the diagnostic value of antineuroneal antibodies in females with subacute neurologic impairment in the form of paraneoplastic syndrome.

  • anti-Yo antibodies
  • fallopian tube carcinoma
  • paraneoplastic syndrome

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