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2022-RA-1090-ESGO Descriptive study of vulvar cancers according to the vulnerability of patients related to age: multicenter study
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  1. Emilie Raimond1,
  2. Caroline Ambroise2,
  3. Camille Mimoun3,
  4. Yohan Kerbage4,
  5. Lobna Ouldamer5,
  6. Sofiane Bendifallah6,
  7. Xavier Carcopino7,
  8. Martin Koskas8,
  9. Pierre Adrien Bolze9,
  10. Vincent Lavoue10,
  11. Tristan Gauthier11,
  12. Olivier Graesslin12,
  13. Arnaud Fauconnier13 and
  14. Cyrille Huchon14
  1. 1Department of Obstetrics and Gynaecology, Institute Alix de Champagne University Hospital, CHU de REIMS, REIMS, France
  2. 2Department of Obstetrics and Gynaecology, Institute Alix de Champagne University Hospital, CHU REIMS, REIMS, France
  3. 3Department of Obstetrics and Gynaecology, Lariboisière, Assistance Publique des Hôpitaux de Paris (AP-HP), Paris, France
  4. 4Department of Obstetrics and Gynaecology, Lille University Hospital, lille, France
  5. 5Department of Obstetrics and Gynaecology, Bretonneau Hospital, TOURS, France
  6. 6Department of Obstetrics and Gynaecology, Tenon Hospital, Paris, France
  7. 7Department of Obstetrics and Gynaecology, North Hospital, Marseille, France
  8. 8Department of Obstetrics and Gynaecology, Bichat Hospital, Paris, France
  9. 9Department of Gynecological Surgery and Oncology, Pierre Bénite Hospices Civils de Lyon, Lyon, France
  10. 10Department of Obstetrics and Gynaecology, University Hospital Center of Rennes, South Hospital, Rennes, France
  11. 11Department of Obstetrics and Gynaecology, Mère – enfant Hospital, University Hospital Center of Limoges, Limoges, France
  12. 12Department of Obstetrics and Gynaecology, Institute Alix de Champagne University Hospital, REIMS, France
  13. 13Department of Obstetrics and Gynaecology, Intercommunal Hospital Center of Poissy, Poissy, France
  14. 14Department of Obstetrics and Gynaecology, lariboisière hospital, Paris, France

Abstract

Introduction/Background The purpose of this study is to assess the impact of age on tumor size in vulvar cancer.

Methodology This is a multicenter retrospective observational study incorporating 447 cases of vulva cancer. A limit age of 65 years was chosen to define the 2 groups of patients to compare.

Results Patients of <65 years more often had an induced HPV cancer history (16.1% (n=27) versus 3.9% (n=11), p <0.001), mainly history of uterus cervical cancer. The location of tumors was also different between the 2 groups. The median clinical and post-operative size of the tumors was 20 mm (1–120) and 26 mm (1–65) in the group of patients under 65 and 30 mm (1–100) and 35 mm (1–66) in patients of> 65 years (p = 0.07 and p = 0.001, respectively). There was no difference concerning the in sano excision between the 2 groups. Multivariate analysis found that age> 65 years (p = 0.02) and a history of cervical cancer (p = 0.01) was greater post-operative risk factors of tumor.

Conclusion Age is a larger tumor size risk factor. In elderly and vulnerable women this can cause post-operative complications altering the quality of life of patients. It is therefore necessary to take into account the vulnerability linked to the age of patients in the overall management of vulvar cancers.

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