Introduction According to GLOBOCAN STATISTICS 2018, Endometrial Carcinoma (EC) is the 6th most common cancer among female population in the world, and the 2nd among all tumors of the female reproductive system. Belarus takes the first place in the world by incidence rate of EC 24.9 per 100,000.

Objective The aim of this study was to estimate incidence rate, mortality and survival rate of newly diagnosed EC in Belarus from 2009 to 2018.

Method We analyzed the data from the Belarusian Cancer Registry.

Results In Belarus, from 2009 to 2018 were diagnosed 19 388 new cases of EC. The standardized incidence rate of EC has increased from 18.7 per 100,000 in 2009 to 24.1 per 100,000 in 2018 (p<0,01).

Comparison of two five year periods (2009–2013 and 2014–2018) showed that the rate of stage I EC increased from 72.6% to 76.6%, respectively. Meanwhile rates of advanced EC (stage III-IV) hasn’t been significantly changed 7,43% and 7,36%, respectively.

Standardized mortality rate in the studied period was 2,98 and 3,3, respectively. Adjustive relative survival rate for stage I EC was 93,1±0,5% and 92,1±0,5%, stage II 75,5±1,9% and 75,6±2%, for stage III 44,1±2,2% and 49,5±2%, for stage IV 15,9±3,3% and 17,3±2,3%, respectively.

Conclusions We did not find significant changes in the survival rate between the studied periods. The level of survival and mortality rate complies with international standards.