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71 The oncological safety of hysteroscopy in the diagnosis of early-stage endometrial cancer: an israel gynecologic oncology group study
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  1. M Volodarsky1,
  2. A Namazov2,
  3. O Gemer2,
  4. L helpman3,
  5. N Hag-Yahia3,
  6. R Eitan4,
  7. O Raban4,
  8. Z Vaknin5,
  9. S Leytes6,
  10. O Lavie7,
  11. A Amit8,
  12. T Levy9,
  13. I Ben Shachar10,
  14. I Atlas11,
  15. I Bruchim12 and
  16. A Ben-Arie13
  1. 1Barzilai Medical Center-, Obstetrics-Gynecology Department, Ashkelon, Israel
  2. 2Barzilai University Medical center- Faculty of Health Science- Ben Gurion University- Ashkelon, obstetrics-gynecology department, Ashkelon, Israel
  3. 3Meir Medical Center- Sackler School of Medicine- Tel Aviv University, obstetrics-gynecology, Kfar Saba, Israel
  4. 4Rabin Medical Center- Sackler School of Medicine- Tel Aviv University-, Obstetrics-gynecology, Petah Tikva, Israel
  5. 5Assaf Haroffe Medical Center- Sackler School of Medicine- Tel Aviv University-, Obstetrics-gynecology, Zrifin, Israel
  6. 6Wolfson Medical Center- Sackler School of Medicine- Tel Aviv University-, obstetrics-gynecology, Holon, Israel
  7. 7Carmel Medical Center- Rappaport Faculty of Medicine- Technion-, Gynecologic oncology, Haifa, Israel
  8. 8Rambam Medical Center- Rappaport Faculty of Medicine- Technion-, Gynecologic oncology, Haifa, Israel
  9. 9Wolfson Medical Center- Sackler School of Medicine- Tel Aviv University-, Gynecologic oncology, Holon, Israel
  10. 10Ziv Medical Center- Bar Ilan University-, obstetrics-gynecology, Zefat, Israel
  11. 11Poriya Medical Center- Bar Ilan University-, obstetric-gynecology, Tiberia, Israel
  12. 12Hillel Yaffe Medical Center- Rappaport Faculty of Medicine- Technion-, obstetrics-gynecology, Hedera, Israel
  13. 13Kaplan Medical Center- Hebrew University-, Obstetric-gynecology, Rehovot, Israel

Abstract

Objectives To compare survival measures of women with early-stage endometrial cancer who underwent either hysteroscopy or a non-hysteroscopic procedure as a diagnostic procedure.

Methods An Israel Gynecologic Oncology Group multicenter study of 1324 patients with stage I endometrial cancer who underwent surgery between 2002 and 2014. Patients were divided into two groups: hysteroscopy and non-hysteroscopy (curettage or office endometrial biopsy). Clinical, pathological, and survival measures were compared between the groups.

Results There were 355 patients in the hysteroscopy group and 969 patients in the non-hysteroscopy group. The median follow-up was 52 months (range 12–120 months). There were no differences between the groups in the 5-year recurrence-free survival (90.2% vs. 88.2%; p=0.53), disease-specific survival (93.4% vs. 91.7%; p=0.5), and overall survival (86.2% vs. 80.6%; p=0.22).

Conclusions Our findings affirm that hysteroscopy does not compromise the survival of patients with early-stage endometrial cancer.

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